Sometimes, people like drugs or need drugs so much; they can't do without them.

有时，人们喜欢毒品或非常需要毒品，他们离不开毒品。

youdao

She can't do without a secretary.

她不能没有秘书。

《牛津词典》

We can't do without the help of your organization.

我们不能没有你们机构的帮助。

《柯林斯英汉双解大词典》

Lo-and-behold,you can't do anything without a WWW.Nothing,".

VOA: standard.2010.01.05

He's a better teacher than Scotus or Aquinas, and the text seems almost to suggest that Milton can't do without his own teacher, Edmund Spenser.

他是一位比苏格拉底和阿奎那更好的良师，这些文章几乎暗示了弥尔顿,没有老师埃蒙德·斯潘塞则不能做到弃绝那些诱惑。

耶鲁公开课 - 弥尔顿课程节选

In other words, in a certain sense you can't do without it.

换句话说，在某种意义上，不这样做是不行的。

耶鲁公开课 - 文学理论导论课程节选

Ain't it true, there's just no doubt, there's some things that you can't do without.

NPR: The '80s Strike Back: Devo's Mark Mothersbaugh

And it's an extra that the phone's data-hungry users can't do without.

FORBES: iPhone Fans Score

Both are not only regular but heavy Internet users, who couldn't do their jobs without it, and both have long since forgotten their dismissal of the medium they now can't do without.

FORBES: The Addictive Internet